Figure 5.

Eye blinking frequency in conventional rats treated with oxindole, isatin, or indole. (A) Number of eye blinkings/min during 10 min, from 2 min after i.p. injection of oxindole or isatin (50 and 100 mg/kg) or of the DMSO vehicle (n = 7–8 rats/group, Kruskal-Wallis test followed by a Dunn's multiple comparison test). (B) Number of eye blinkings/min during 10 min, from 2 min after intra-cecal injection of indole (500 mg/kg) or of the corn oil vehicle (n = 12 rats/group, Mann-Whitney test). Data are medians with interquartile ranges. ^***P < 0.001.