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. 2018 Feb 28;15(3):235–245. doi: 10.30773/pi.2017.08.17

Table 1.

Heart rate variability (HRV) time-domain measures [15]

Variable Units Description
Statistical measures
 SDNN ms Standard deviation of all NN intervals
 SDANN ms Standard deviation of the averages of NN intervals in all 5-minute segments of the entire recording
 RMSSD ms The square root of the mean of the sum of the squares of differences between adjacent NN intervals
 SDNN index ms Mean of the standard deviations of all NN intervals for all 5-minute segments of the entire recording
 SDSD ms Standard deviation of differences between adjacent NN intervals
 NN50 count Number of pairs of adjacent NN intervals differing by more than 50 ms in the entire recording; three variants are possible counting all such NN intervals pairs or only pairs in which the first or the second interval is longer
pNN50 % NN50 count divided by the total number of all NN intervals
Geometric measures
 HRV triangular index Total number of all NN intervals divided by the height of the histogram of all NN intervals measured on a discrete scale with bins of 7.8125 ms (1/128 seconds)
 TINN ms Baseline width of the minimum square difference triangular interpolation of the highest peak of the histogram of all NN intervals
 Differential index ms Difference between the widths of the histogram of differences between adjacent NN intervals measured at selected heights (e.g., at the levels of 1,000 and 10,000 samples)
 Logarithmic index Coefficient φ of the negative exponential curve k · e−φt, which is the best approximation of the histogram of absolute differences between adjacent NN intervals

NN: normal-to-normal