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. 2018 Feb 28;15(3):306–312. doi: 10.30773/pi.2017.07.24

Table 2.

The effects of genetic polymorphism (-1291C/G) and clinical demographics on the MPH response

Independent variables OR 95% CI p-value
Gender 0.80 0.84–7.78 0.85
Age 0.92 0.62–1.37 0.69
BMI 1.33 0.99–1.78 0.05
Daily dose (mg/day) 1.01 0.93–1.10 0.68
Genotype
 C/G vs. C/C 0.0001 0.0001–NA 0.99
 G/G vs. C/C 0.0001 0.0001–NA 0.99

The subjects received MPH treatment were categorized as non-responders and responders and subjected to binary logistic regression analysis. Those with more than 25% reduction in the SNAPIV total scores were referred as responders. OR: odds ratio, CI: confidence interval, MPH: methylphenidate, BMI: body mass index, NA: not available, SNAP-IV: Swanson, Nolan and Pelham version IV