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. 2018 Apr 9;5:88. doi: 10.3389/fmed.2018.00088

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Copyright © 2018 Carter, Carter, Saschenbrecker and Goeckeritz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of autoantibody profiling by line immunoassay in serum samples with a typical dense fine speckled (DFS) pattern (AC-2) in indirect immunofluorescence (IIF). Percentages for anti-DFS70 positive (blue) and negative (red) results by LIA refer to the total number DFS IIF positive cases (green). The likelihood for the presence or development of an associated systemic autoimmune rheumatic disease (SARD), in accordance with Conrad et al. (19), is indicated in the outermost circle (white). (+), positive; (±), borderline; (−), negative.