Table 3. Comparative analysis of synovial fluid and serum cartilage oligomeric matrix protein levels by sex.

	SF COMP (n=151)			Serum COMP (n=152)
	Median	Min-Max	p	Median	Min-Max	p
Total levels of COMP (ng/mL)	676,6	25-2480	0.033*†	257,5	18-2542	0.035*†
KOA	777	50-2480		314	18-2542
Control group	676,3	25-836		228	57-810
Female KOA (ng/mL)	891,2	50-2420	0.007*†	296	18-2230	0.116†
Female healthy individuals	676,3	25-817,5		201	61-801
Male KOA (ng/mL)	529	58-2480	0.875†	343	32-2542	0.146†
Male healthy individuals	676,3	173-836		257,5	57-810
SF: Synovial fluid; COMP: Cartilage oligomeric matrix protein; Min: Minimum; Max: Maximum; KOA: Knee osteoarthritis; † Mann Whitney U test; * Significant if p<0.05; ** Significant if p<0.01.