Table 4. Comparison between synovial fluid, serum levels of cartilage oligomeric matrix protein, and different Kellgren-Lawrence grades.

	Mild (n=14)		Moderate (n=50)		Severe (n=41)
	Median	Min-Max	Median	Min-Max	Median	Min-Max	p
Synovial fluid COMP (ng/mL)	325,5	50-1549	765,5	85-2420	891,5	165-2480	0.012*†
	Mild (n=13)		Moderate (n=41)		Severe (n=21)
	Median	Min-Max	Median	Min-Max	Median	Min-Max	p
Serum COMP (ng/mL)	296	32-2542	445	65-2230	195	18-1581	0.121†
Min: Minimum; Max: Maximum; COMP: Cartilage oligomeric matrix protein; † Kruskal-Wallis test; * Significant if p<0.05.