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. 2018 Apr 9;6:93. doi: 10.3389/fped.2018.00093

Table 2.

Comparison of outcomes between the “PALICC only” and the “Berlin with or without PALICC” definition groups.

Variable “PALICC only” group (N = 35) “Berlin with or without PALICC” group (N = 26) p-Value
Proportion of patients with failed non- invasive ventilation at diagnosis (N, %) 3 (8.5%) 5 (19%) 0.236
Duration of mechanical ventilation (hrs.) (Median, IQR)
  • –

    Total duration

 7 (3.8, 14) 8 (4, 12) 0.816
  • –

    Duration of ventilation for acute respiratory distress syndrome (ARDS)

 6 (3.8, 10) 7 (2, 12) 0.980
  • –

    Proportion of patients requiring HFOVa (N, %)

 4 (13.3) 9 (29) 0.023
  • –

    Duration of HFOVa (hrs) (Median, IQR)

 2.5 (0.3, 2.5) 3 (0.4, 7) 0.547
Air leaks (N, %) 2 (6.7) 7 (22.5) 0.021
  • –

    Need for Vasoactive therapy (N, %)

 28 (80) 25 (96.1) 0.065
  • –

    Duration of Vasoactive therapy (hrs.) (Median, IQR)

 52 (24, 96) 18 (7, 72) 0.203
Need for dialysis (N, %) 10 (28.6) 5 (19.2) 0.548
  • –

    Use of steroids (N, %)

 22 (62.8) 21 (80.8) 0.171
  • –

    Duration of steroids use (days) (Median, IQR)

 4.4 (2, 8) 4.8 (1.3, 12) 0.772
Duration of ICUb stay (days) (Median, IQR) 7 (5, 14) 8 (4, 13) 0.775
Duration of hospital stay (days) (Median, IQR) 13 (7, 18) 12 (5, 23) 0.898
PELOD Score (Median, IQR)
  • –

    Day 2

 20 (11, 22) 11.5 (3, 22) 0.245
  • –

    Day 5

 11.5 (1, 21) 11 (2, 11) 0.327
  • –

    Mortality (N, %)

 18 (51.4) 15 (58) 0.966
  • –

    Mortality due to ARDS (N, %)

 3 (9) 7 (27) 0.104
  • –

    Mortality due to nosocomial sepsis (N, %)

 8 (23) 4 (15) 0.49

aHFOV, high-frequency oscillatory ventilation; bICU, intensive care unit.