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. 2018 Mar;13(3):484–491. doi: 10.4103/1673-5374.228732

Figure 9.

Figure 9

Effect of on acetyl-11-keto-β-boswellic acid (AKBA) or PD98059 on phospho-extracellular signal-regulated kinase 1 and 2 (p-ERK1/2) expression and cell proliferation of Schwann cells.

(A) p-ERK1/2 expression in Schwann cells treated without AKBA or PD98059 (control group), with ERK1/2 inhibitor PD98059 only, 2 µg/mL AKBA only, or 2 µg/mL AKBA + 2.5 μL/mL PD98059. (B) p-ERK1/2 expression was quantified from different groups by western blot assay. Relative p-ERK 1/2 expression was expressed by a ratio of optical density values of p-ERK1/2 to ERK1/2. (C) Quantitative results of cell proliferation detected by CCK-8 colorimetry assay. Cell proliferation was expressed as a ratio of optical density values of target group to control group (0 µg/mL). Data were expressed as the mean ± SD and analyzed by t-test. *P < 0.05, **P < 0.01, vs. control group.