Figure 5.

Impact of Y-27632 on the migration ability of Müller cells under hypoxia and oxidative stress.

(A–E) Control, CoCl₂, CoCl₂ + Y-27632, H₂O₂ and H₂O₂ + Y-27632 groups, respectively (original magnification, 100×). Control group: Migrating cells are rare. CoCl₂ and H₂O₂ groups: the number of migrating cells increases, and Y27632 suppresses migration. (F) Quantitation of the migration ability of Müller cells. Arrows indicate migrated cells. Data are expressed as the mean ± SD and were analyzed by one-way analysis of variance followed by the least significant difference test. All experiments were performed in triplicate. #P < 0.05, ##P < 0.01, vs. control group.