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. 2018 Apr 9;9:112. doi: 10.3389/fgene.2018.00112

Table 5.

Results of multivariate analysis of the APOA5 rs2072560, rs2266788 and rs662799 with triglycerides (TG) and Very Low-Density Lipoprotein (VLDL) levels in the cohort (n = 733).

Variable OR 95% C.I. p-value
TG
(RF allele: G) rs2072560 G/A 1.09 (0.98–1.22) 0.12
rs2072560 A/A 1.42 (1.03–1.95) 0.03*
Sex (M) 1.27 (1.16–1.39) 2.11E-07*
Age 1.01 (1.01–1.02) 2.81E-15*
BMI 1.02 (1.02–1.03) 2.44E-11*
(RF allele: T) rs2266788 T/C 1.15 (1.03–1.27) 0.01*
rs2266788 C/C 1.24 (0.93–1.67) 0.13
Sex (M) 1.28 (1.17–1.40) 1.26E-07*
Age 1.01 (1.01–1.02) 2.23E-15*
BMI 1.02 (1.02–1.03) 2.88E-11*
(RF allele: T) rs662799C/T 0.9 (0.82–1) 0.05
rs662799T/T 0.73 (0.58–0.92) 0.01*
Sex (M) 1.27 (1.16–1.39) 4.89E-07*
Age 1.02 (1.01–1.02) 4.0E-15*
BMI 1.02 (1.02–1.03) 1.29E-11*
VLDL
(RF allele: G) rs2072560 G/A 1.09 (0.98–1.23) 0.11
rs2072560 A/A 1.42 (1.03–1.97) 0.03*
Sex (M) 1.27 (1.15–1.39) 1.02E-06*
Age 1.02 (1.01–1.02) < 2E-16*
BMI 1.02 (1.02–1.03) 2.22E-11*
(RF allele: T) rs2266788 T/C 1.14 (1.02–1.27) 0.02*
rs2266788 C/C 1.25 (0.92–1.68) 0.15
Sex (M) 1.27 (1.16–1.39) 6.05E-07*
Age 1.02 (1.01–1.02) < 2E-16*
BMI 1.02 (1.02–1.03) 2.84E-11*
(RF allele: C) rs662799C/T 0.9 (0.81–1) 0.05
rs662799T/T 0.78 (0.61–1) 0.05
Sex (M) 1.27 (1.15–1.39) 9.73E-07*
Age 1.02 (1.01–1.02) <2E-16*
BMI 1.03 (1.02–1.03) 1.12E-11*

RF: Reference allele. The values represented include the odds ratio, confidence interval and p values as evaluated by multivariate logistic regression in 511 Kuwaiti individuals. It shows the mentioned variants to be a significant

*

(p < 0.05) independent predictive factor when controlling for age, sex and BMI for both TG and VLDL. Significant values (p < 0.05) are highlighted.