FIGURE 8.
Normalized distributions of AEG-1 clusters in transmembrane protein mRNAs. Plots depicting cluster distributions flanking the start codon (A,B) and stop codon (C,D) of mRNAs encoding cytosolic, transmembrane, or secretory proteins, in the HITS-CLIP (A,C) and PAR-CLIP (C,D) experiments. (E,F) Plots depicting cluster distributions flanking encoded transmembrane domains (E), the transmembrane domains of Type I membrane proteins (F), or relative to subsequent transmembrane domains (G), for the HITS-CLIP and PAR-CLIP data sets. Cluster enrichment data are plotted as cluster density where 0 indicates the first nucleotide of start codons, stop codons, or transmembrane domain-encoding regions.