Figure 7.

Differential effect of mutations on Pt(NO₂)₄²⁻ block. A, example macroscopic current–voltage relationships for different channel variants in inside-out patches. In each case currents were recorded before (control, black) and after (red) addition of 50 μm Pt(NO₂)₄²⁻ to the intracellular solution. B, mean fraction of control current remaining following addition of this concentration of Pt(NO₂)₄²⁻ as a function of voltage in these channel variants. The means of data from 5–7 patches are shown.