Table 2.

Structural analysis of SARAH domain dimers

General			Superpositions			Helical analysis		Buried surface area (BSA) (Å2)
SARAH domain dimers	PDB code	Chain IDs of dimers	R.m.s. deviation (Å)	Residue range chain 1	Residue range chain 2	Chain 1	Chain 2
Hippo/Salvadora	6BN1	A, B	0	615–654	581–620	Kinked	NK-Lb	3358
Mst2/RassF5 (26)	4LGD	A, E	1.9	445–484	374–412	Kinked	NK-L	2755
Mst2/RassF5 (26)	4LGD	B, F	NAc	NA	NA	Kinked	NK-L	1483
Mst2/RassF5 (26)	4LGD	C, G	0.9	445–484	374–412	Kinked	NK-Cd	2863
Mst2/RassF5 (26)	4LGD	D, H	NA	NA	NA	Kinked	NK-L	2106
Mst1/RassF5 (33)	4OH8	A, B	1.1	12–51	9–47	Kinked	NK-L	2402
Mst2	3WWS	A, B	1.8	445–484	445–484	Kinked	Kinked	2912
Mst2	3WWS	C, D	1.8	445–484	445–484	Kinked	Kinked	2815
Mst2 (33)	4OH9	A, B	1.3	12–51	12–51	Kinked	NK-L	3069
Mst1	4NR2	A, B	1.8	441–480	441–480	Kinked	Kinked	2759
Mst1	4NR2	C, D	1.8	441–480	441–480	Kinked	Kinked	2830
Mst1	4NR2	E, F	1.6	441–480	441–480	Kinked	Kinked	2749
Mst1	4NR2	G, H	1.9	441–480	441–480	Kinked	Kinked	2846
Mst2	4HKD	A, B	1.3	445–484	445–484	Kinked	Kinked	2901
Mst2	4HKD	C, D	1.3	445–484	445–484	Kinked	Kinked	2992
Mst2	4L0N	A, B	2.1	445–484	445–484	Kinked	Kinked	2861
Mst2	4L0N	C, D	1.9	445–484	445–484	NK-L	Kinked	2934
Mst2	4L0N	E, F	2.3	445–484	445–484	NK-C	Kinked	2799
Mst2	4L0N	G, H	2.0	445–484	445–484	NK-C	Kinked	2850
Mst2	4L0N	I, I*e	2.5	445–484	445–484	Kinked	Kinked	1911
Mst2	4L0N	J, J*e	2.0	445–484	445–484	NK-L	NK-L	1894
Mst1 (29)	2JO8	A, B	2.4	369–408	369–408	Kinked	Kinked	2795
Nore1 (34)	2YMY	A, B	2.2	369–408	369–408	NK-L	NK-L	1768

^a Current work.

^b Not kinked, curved (NK-C).

^c α-Helices were of insufficient length to compare.

^d Not kinked, linear (NK-L).

^e *, represents a second chain generated by crystal symmetry.