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ST6Gal-I knockdown in MiaPaCa-2 cells decreases the hypoxia-induced transcription of HIF-1α target genes. A–D, MiaPaCa-2 ShC and KD cells were grown in normoxia or hypoxia for 12 or 24 h, and then RT-qPCR was used to measure the expression of GLUT1 (A), GLUT3 (B), PDHK1 (C), and VEGFα (D). Graphs depict means and S.D.s from at least three independent experiments. *, p < 0.05.
