Table 3.
Grade of evidence for effect | Symptoms/indications | Meaning for physicians |
---|---|---|
High |
Overall symptoms and abdominal pain in IBS Prevention or reduction of diarrhoea in patients receiving antibiotics Prevention or reduction of diarrhoea in patients receiving Helicobacter pylori eradication therapy |
Probiotics with supportive evidence for benefit should be tried |
Moderate | Bowel movements and bloating/distension in IBS | Probiotics with supportive evidence for benefit could be tried |
Low |
Overall symptoms in IBS‐D Flatus in IBS Constipation in IBS |
Probiotics with supportive evidence for benefit could be considered |
Very low |
Overall symptoms in IBS‐C Diarrhoea in IBS |
Currently no evidence to support use of probiotics |
IBS, irritable bowel syndrome; IBS‐C, constipation‐predominant IBS; IBS‐D, diarrhoea‐predominant IBS.