Figure 1.

Adult GAERS TRN neurons display sustained oscillatory burst‐firing at 6‐9 Hz. A, Representative traces showing response of adult NEC (A—upper panel) and GAERS (A—middle panel) TRN neurons to a 2 second sinusoidal current injection stimulus (A—lower panel). Stimulus magnitude was incrementally increased until bursting (>3 action potentials) occurred on 3 initial bursts. Scale bars = 30 mV, 100 msec. B, The sinusoidal stimulus was applied at variable frequencies (5‐10 Hz), with the number of action potentials per burst decreasing with time. Insets show representative voltage traces of the last burst in a series. 6 Hz: NEC = 31.2 ± 6.2%, GAERS = 52.8 ± 7.8, P = .034 t test; 7 Hz: NEC = 23.6 ± 4.4%, GAERS = 43.3 ± 7.2%, P = .044 t test; 8 Hz: NEC = 22.7 ± 5.1%, GAERS = 40.3 ± 6.4%, P = .047 t test; 9 Hz: NEC = 30.1 ± 5.9%, GAERS = 56.2 ± 3.7%, P = .005 t test. NEC (n = 20 cells, n = 11 animals), GAERS (n = 15 cells, n = 10 animals). Scale bars represent 20 msec and 10 mV. *P < .05