Table 2.
Baseline characteristics of the cases and their sex, age, and CFTR matched controls before S. maltophilia initial infection
| Cases (n = 23) | Controls (n = 23) | P‐value a | |
|---|---|---|---|
| Age (yrs), mean (SD) | 8.8 (5.3) | 8.9 (5.0) | 1 |
| Sex (male/female) | 8/15 | 8/15 | 1 |
| CFTR F508 del homozygous, % (n) | 48% (11) | 52% (12) | 1 |
| FEV1pp, mean (SD) | |||
| 2 years before S. maltophilia infection | 83 (17) | 91 (18) | 0.25 |
| 1 year before S. maltophilia infection | 72 (21) | 89 (20) | 0.13 |
| At S. maltophilia infection | 71 (20) | 90 (21) | 0.05* |
| BMI (Z‐score), mean (SD) | −0.88 (1.01) | −0.15 (0.73) | 0.09 |
| Annual rates of respiratory exacerbations, mean (SD) | 3.0 (1.6) | 1.6 (1.5) | 0.01* |
| Annual rates of hospitalizations, mean (SD) | 0.71 (1.01) | 0.11 (0.32) | 0.02* |
| Number of patients with intravenous antibiotic courses, % (n) | 34.7% (8) | 8.6% (2) | 0.04* |
| P. aeruginosa colonization, % (n) | 13% (3) | 0% (0) | 0.25 |
| MRSA colonization, % (n) | 13% (3) | 0% (0) | 0.25 |
The data are the means (SD) or % (numbers) unless otherwise indicated.
FEV1pp, forced expiratory volume in one second percent predicted; BMI, body mass index; P. aeruginosa, Pseudomonas aeruginosa; MRSA, methicillin‐resistant Staphyloccocus aureus.
a
For the comparison of sex, age, and CFTR matched cases and controls.
*P < 0.05.