Figure 4.

CRF₂ receptor deficiency does not affect SNP. (A) SNP ratio (%) displayed by saline (SAL)‐ or cocaine (COC)‐treated wild‐type and CRF₂−/− mice. The three‐chamber tests were carried out immediately (0), 7 and 14 days after the last saline or cocaine administration. (B) Total entries made into the two side compartments of the three‐chamber apparatus during the SNP test. The n for each experimental group is presented in panel B. Values represent mean ± SEM. ^### P < 0.05 versus saline groups on day 0, genotype‐independent effect.