TABLE 8.

Estimated Mean Volume (mm3 ± SE) of Examined Structures and Cytoarchitectonic Subdivisions in 1 Brain Hemisphere and Correlation Between Volume and Age

Structures and Their Subdivisions	Age: 25–102		Age 25–63		Age 69–102
	Volume	Pearson Correlation with Age	Volume	Pearson Correlation with Age	Volume	Pearson Correlation with Age
Entorhinal c. (All layers)	593 ± 23	−0.53; p = 0.022	650 ± 32	ns	531 ± 24	ns
Entorhinal c. (Islands)	35 ± 2	−0.57; p = 0.015	40 ± 2	ns	29 ± 1	ns
CA1	423 ± 14	ns	450 ± 16	ns	389 ± 21	ns
CA2	36 ± 1	ns	34 ± 2	ns	39 ± 2	ns
CA3	45 ± 2	ns	45 ± 2	ns	45 ± 3	ns
CA4	105 ± 5	ns	110 ± 7	ns	100 ± 6	ns
CA (1–4)	610 ± 18	ns	639 ± 21	ns	572 ± 28	ns
Subiculum*	188 ± 8	ns	194 ± 10	ns	180 ± 12	ns
Amygdala†	446 ±15	ns	470 ±15	ns	420 ± 20	ns
Thalamus	3023 ± 122	−0.78; p = 0.0015	3406 ± 114	ns	2640 ± 130	ns
Magnocellular basal complex‡	128 ± 4	ns	134 ± 5	ns	120 ± 5	ns
Caudate nucleus	1975 ± 59	ns	2018 ± 93	ns	1929 ± 71	ns
Substantia nigra§	90 ± 5	ns	97 ± 6	ns	82 ± 6	ns
Cerebellum	24 514	ns	25 451 ± 1618	ns	23 747 ± 1438	ns
Dentate nucleus	323 ±14	−0.54; p = 0.015	364 ± 14	ns	271 ± 15	ns

Volume (mm3), total volume calculated using mounted section thickness.

^*Subiculum, total volume of the subiculum proper.

^†Amygdala, total volume of lateral, basal, accessory and central nuclei.

^‡Magnocellular basal complex: total volume of Ch1-4.

^§Substantria nigra, total volume of the pars compacta and reticulata.

p values incorporate adjustment to set false discovery rate at 0.05.