Table 5.
Inheritance analysis of rs6062251 in pri-miR-133a-2 between NSCLC and control groups (after adjusting for gender and age)
| Model | Genotype | Control, n (%) | NSCLC, n (%) | OR (95% CI) | P-value | AIC | BIC |
|---|---|---|---|---|---|---|---|
| Codominant | T/T | 211 (46.7) | 192 (42.5) | 1.00 | 0.340 | 1338.9 | 1608.1 |
| C/T | 195 (43.1) | 217 (48) | 1.23 (0.92–1.64) | ||||
| C/C | 46 (10.2) | 43 (9.5) | 1.01 (0.63–1.63) | ||||
| Dominant | T/T | 211 (46.7) | 192 (42.5) | 1.00 | 0.220 | 1337.5 | 1601.9 |
| C/T-C/C | 241 (53.3) | 260 (57.5) | 1.19 (0.90–1.56) | ||||
| Recessive | T/T-C/T | 406 (89.8) | 409 (90.5) | 1.00 | 0.690 | 1338.9 | 1603.3 |
| C/C | 46 (10.2) | 43 (9.5) | 0.91 (0.58–1.44) | ||||
| Overdominant | T/T-C/C | 257 (56.9) | 235 (52) | 1.00 | 0.140 | 1336.9 | 1601.3 |
| C/T | 195 (43.1) | 217 (48) | 1.23 (0.93–1.61) | ||||
| Log-additive | – | – | – | 1.08 (0.88–1.34) | 0.450 | 1260.4 | 1279.6 |
Abbreviations: AIC, Akaike information criterion; BIC, Bayesian information criterion; NSCLC, nonsmall cell lung cancer.