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(a) The median Jaccard similarity indices for 1,000 randomizations (maintaining connectedness). Observed median Jaccard similarity (red arrow) is 0.0204, corresponding to a p‐value of 0.036. Using randomizations that do not maintain connectedness, p = 0.006. (b) The maximum Jaccard similarity indices for 1,000 randomizations (maintaining connectedness). Observed median Jaccard similarity (red arrow) is 0.228, corresponding to a p‐value <0.001
