Table 4. Receiver operating characteristic curve areas, cut-offs, sensitivity, and specificity for the PDT, MMSE, MMSE plus the PDT and the CAMCOG between AD and NC groups.
AUC* | Cut-off** | Sensitivity | Specificity | 95% CI | |
---|---|---|---|---|---|
PDT | 0.784 | ≥ 5 | 95.2% | 45.9% | 0.738-0.828 |
MMSE | 0.975 | ≥ 25 | 96% | 90.2% | 0.960-0.991 |
MMSE + PDT# | 0.973 | ≥ 30 | 95.2% | 90.2% | 0.957-0.989 |
CAMCOG | 0.970 | ≥ 78 | 97.6% | 88.7% | 0.954-0.986 |
PDT: Pentagon Drawing Test; MMSE: Mini-Mental State Examination; CAMCOG: Cambridge Cognitive Test; NC: normal control; AD: Alzheimer's disease;
p <0.001 for PDT vs MMSE and PDT vs CAMCOG;
cut-off for best balance between sensitivity and specificity for this sample;
The traditional score of 0 or 1 point for the pentagon drawing was substituted by Bourke et al. scoring scale with 0 to 6 points. Thus, MMSE total score was 35 points. 95% CI : Asymptotic 95% Confidence Interval.