Table 2. Genes and isoforms ≥ ± 1.5-fold (up-regulated and down-regulated), differentially expressed in longissimus dorsi muscle of Polish Landrace pigs.
Gene | Ensembl ID | DESeq | edgeR | baySeq FDR | Validation qPCR PC 1 | ||||
---|---|---|---|---|---|---|---|---|---|
r | P | ||||||||
Symbol | Name | FC | Ad P-value | FC | FDR | ||||
PPP1R11 | Protein phosphatase 1, regulatory (inhibitor) subunit 11 | ENSSSCG00000028347 | 2.40 | *** | 5.13 | *** | *** | 0.63 | ≤0.05 |
CNN1 | calponin 1, basic, smooth muscle | ENSSSCG00000013614 | 2.06 | *** | 2.60 | *** | *** | 0.89 | ≤0.001 |
NG | Similar to NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, (NDUFA6) | ENSSSCG00000021119 | 2.05 | * | 4.46 | ** | *** | ||
PVALB | Parvalbumin | ENSSSCG00000000138 | 1.91 | * | 4.26 | * | * | 0.97 | ≤0.001 |
NG | Similar to transmembrane protein 106C (TMEM106C) | ENSSSCG00000028397 | 1.88 | * | 2.75 | * | 0.057 | ||
CIB2 | Calcium and integrin binding family member 2 | ENSSSCG00000001762 | 1.81 | ** | 2.12 | * | *** | ||
CHPT1 | Cholinephosphotransferase 1 | ENSSSCG00000000864 | 1.66 | * | 1.86 | 0.051 | * | ||
TFDP2 | Transcription factor Dp-2 | ENSSSCG00000026809 | 1.58 | ** | 1.66 | 0.17 | ** | ||
UBE2J1 | Ubiquitin-conjugating enzyme E2 J1 | ENSSSCG00000004317 | 1.55 | * | 1.62 | 0.254 | * | ||
IGLC | Ig lambda chain C region | ENSSSCG00000010044 | -1.48 | 0.321 | -8.06 | * | *** | ||
BCAR3 | Breast cancer anti-estrogen resistance protein 3 | ENSSSCG00000006893 | -1.80 | ** | -2.09 | 0.055 | ** | ||
OAS2 | 2’-5’-oligoadenylate synthase 2 | ENSSSCG00000009881 | -1.91 | * | -3.04 | * | * | 0.91 | ≤ 0.001 |
HP | Haptoglobin | ENSSSCG00000002749 | -1.95 | * | -5.34 | * | *** | 0.92 | ≤ 0.001 |
NG | Similar to cytochrome P450 family 4 subfamily F member 3hydroxylase 1 (CYP4F3 or CYP4F55) | ENSSSCG00000028753 | -1.96 | * | -3.11 | * | *** | ||
SEPT6-007 | 6-isoform of septin 6 | ENSSSCT00000013798 | -1.76 | * | -2.11 | * | * |
Abbreviation: Ad P–value -adjusted P-value, FDR– false discovery rate; P-value: ***P<0.001, **P<0.01, *P<0.05, FC– fold change, PL– Polish Landrace pigs, NG– novel gene according to Ensembl browser,
Pearson correlation coefficient r