Table 4. Functional annotation of differentially expressed genes in semimembranosus muscle of pigs.
| Gene ontology | P-value | Corrected P-value | Genes | |
|---|---|---|---|---|
| up-regulated in Pulawska | up-regulated in Polish Landrace | |||
| Gene ontology | ||||
| GO:0007018 microtubule-based movement | 8.43E-06 | 4.23E-03 | AP2B1, UCHL1 | TTC21B, DNAH11, KIF23, SSX2IP |
| GO:0032989 cellular component morphogenesis | 1.21E-05 | 4.81E-03 | LIMK1, UCHL1, | ENSSSCG00000016843, HES1, SFRP2, TTC21B, FRMD6, TCHP, CDH11, NR4A2, SSX2IP |
| GO:0009056 catabolic process | 3.62E-05 | 7.78E-03 | CTSD, RGP1, HSL, UCHL1, HP, GPX3, OAS2, MAOB, KHK, ISG15 | COL11A1, ALDH1L2, VCAN, HECTD2 |
| GO:0030705 cytoskeleton-dependent intracellular transport | 1.51E-04 | 1.45E-02 | UCHL1 | TTC21B, KIF23, SSX2IP |
| GO:0048565 digestive tract development | 2.54E-04 | 2.06E-02 | ASS1 | KIT, HES1, SFRP2 |
| GO:0097367 carbohydrate derivative binding | 6.08E-04 | 3.46E-02 | SEPT6, LIMK1, ASS1, KHK, HP, OAS2 | KIT, VCAN, CHEK1, DNAH11, KIF23, HELQ, NRK |
| GO:0007155 cell adhesion | 3.18E-03 | 6.50E-02 | ASS1, APOD | KIT, VCAN, HES1, SFRP2, CDH11, SSX2IP, PCDH17 |
| GO:0015485 cholesterol binding | 3.18E-03 | 6.50E-02 | APOD, LXRA | |
| GO:0030199 collagen fibril organization | 3.34E-03 | 6.50E-02 | COL11A1, SFRP2 | |
| GO:0006508 proteolysis | 1.81E-02 | 1.14E-01 | CST6, CTSD, LXRA, ISG15, UCHL1, HP | LXN, SFRP2, HECTD2 |
| GO:0045444 fat cell differentiation | 9.75E-03 | 1.14E-01 | NR4A2, HES1, SFRP2 | |
| GO:0048638 regulation of developmental growth | 2.48E-02 | 1.26E-01 | LIMK1, RNPEPL1 | NRK |
| GO:0034332 adherens junction organization | 2.66E-02 | 1.26E-01 | APOD | CDH11 |
| GO:0031397 negative regulation of protein ubiquitination | 3.22E-02 | 1.32E-01 | LIMK1, ISG15 | |
| GO:0032496 response to lipopolysaccharide | 3.31E-02 | 1.32E-01 | MAOB, LXRA, ASS1 | |
| GO:0042692 muscle cell differentiation | 3.74E-02 | 1.32E-01 | UCHL1 | KIT, HES1, SFRP2 |
| GO:0005509 calcium ion binding | 4.13E-02 | 1.76E-01 | PCDH17, VCAN, CDH11 | |
| GO:0030036 actin cytoskeleton organization | 4.51E-02 | 2.39E-01 | LIMK1 | FRMD6, KIF23 |
| Pathway | ||||
| R-SSC-8866427 VLDLR internalization and degradation | 4.04E-03 | 2.64E-02 | LXRA, AP2B1 | |
| ssc04390 hippo signaling pathway | 4.13E-03 | 3.29E-02 | PPP1R11, FRMD6 | |
| R-SSC-73923 lipid digestion, mobilization, and transport | 1.42E-03 | 4.43E-02 | HSL, LXRA, AP2B1 | |
| R-SSC-174824 lipoprotein metabolism | 7.15E-03 | 1.05E-01 | LXRA, AP2B1 | |
| R-SSC-1442490 collagen degradation | 8.88E-03 | 1.14E-01 | CTSD | COL11A1 |
| R-SSC-804914 transport of fatty acids | 1.91E-02 | 1.16E-01 | APOD | |
| ssc04910 insulin signaling pathway | 3.78E-02 | 1.37E-01 | EXOC7, HSL | |
| ssc00590 arachidonic acid metabolism | 3.56E-02 | 1.37E-01 | GPX3 | |
| R-SSC-5627117 Rho GTPases Activate ROCKs | 3.79E-02 | 1.37E-01 | LIMK1 | |
Functional analysis performed in Kobas 3.0 and Panther Gene List