. 2018 Feb 19;41(1):154–166. doi: 10.1590/1678-4685-GMB-2017-0091

Table 3. Results related to splenic phagocytosis evaluation.

Experimental groups	Phagocytosis
	Absolute values	Mean ± SE
LOT 1
NC	221	44.2 ± 0.66
IR-01 12 mg/kg	228	45.6 ± 1.77ª
IR-01 24 mg/kg	316	63.2 ± 1.28ª^*
IR-01 48 mg/kg	369	73.8 ± 1.15ª^*
LOT 2
DOX	670	134.0 ± 1.37ª^*
+IR-01 12 mg/kg	321	64.2 ± 1.59^b*
+IR-01 24 mg/kg	405	81.0 ± 1.30^b*
+IR-01 48 mg/kg	373	74.6 ± 1.43^b*
LOT 3
CIS	269	53.8 ± 1.35ª^*
+IR-01 12 mg/kg	106	21.2 ± 1.35^c*
+IR-01 24 mg/kg	74	14.8 ± 1.02^c*
+IR-0148 mg/kg	54	10.8 ± 0.86^c*
LOT 4
CPP	515	103.0 ± 2.00ª^*
+IR-01 12 mg/kg	275	55.0 ± 3.46^d*
+IR-01 24 mg/kg	316	63.2 ± 2.57^d*
+IR-01 48 mg/kg	534	106.8 ± 3.13^d

SE: Standard error of the mean; NC: Negative control group; DOX: Doxorubicin group; CIS: Cisplatin group; CPP: Cyclophosphamide group. ^(a)Statistically compared to the NC group; ^(b)Statistically compared to the DOX group; ^(c)Statistically compared to the CIS group; ^(d)Statistically compared to the CPP group; ^*statistically different (p < 0.05; Student’s t-test).