Table 5. Cell death evaluation on mice kidneys and liver.

	Liver		Kidneys
Experimental Groups	Number of dead cells	Mean ± SE	Number of dead cells	Mean ± SE
LOT 1
NC	88	17.6 ± 1.03	63	12.6 ± 0.81
IR-01 12 mg/kg	149	29.8 ± 1.93a*	129	25.8 ± 1.24a*
IR-01 24 mg/kg	215	43.0 ± 1.93a	196	39.20.58a*
IR-01 48 mg/kg	279	55.8 ± 0.86a*	245	49.0 ± 1.04a*
LOT 2
DOX	499	99.8 ± 2.55a*	176	35.2 ± 2.57a*
+IR-01 12 mg/kg	779	1552.57b*	358	71.6 ± 3.40b*
+IR-01 24 mg/kg	610	122 ± 1.84b*	291	58.2 ± 1.39b*
+IR-01 48 mg/kg	565	113 ± 2.12b*	246	49.2 ± 2.28b*
LOT 3
CIS	622	124.4 ± 6.03a*	528	1051.72a*
+IR-01 12 mg/kg	402	80.4 ± 5.92c*	297	59.4 ± 1.03c*
+IR-01 24 mg/kg	247	49.4 ± 3.80c*	221	44.2 ± 2.08c*
+IR-01 48 mg/kg	143	28.6 ± 2.42c*	197	39.4 ± 2.92c*
LOT 4
CPP	614	122 ± 3.36a*	588	117 ± 1.16a*
+IR-01 12 mg/kg	307	61.4 ± 3.95d*	522	104 ± 1.93d*
+IR-01 24 mg/kg	362	72.4 ± 4.63d*	381	76.2 ± 3.35d*
+IR-01 48 mg/kg	197	39.4 ± 5.47d*	377	75.4 ± 2.08d*

SE: Standard error of the mean; NC: Negative control group; DOX: Doxorubicin group; CIS: Cisplatin group; CPP: Cyclophosphamide group. ^(a)Statistically compared to the NC group; ^(b)Statistically compared to the DOX group; ^(c)Statistically compared to the CIS group; ^(d)Statistically compared to the CPP group; ^*statistically different (p < 0.05; Student’s t-test).