Table 1.

Parameter Estimates from Dynamical Systems Model for Each Treatment Group

	Bupropion			Lozenge			Patch			Patch+ Lozenge			Bupropion+ Lozenge			Placebo
Results for Equation (1): Predictors of Cessation Fatigue
	β̂+	β̂	β̂−	β̂+	β̂	β̂−	β̂+	β̂	β̂−	β̂+	β̂	β̂−	β̂+	β̂	β̂−	β̂+	β̂	β̂−
Constant	.353	.305	.257	.246	.230	.214	.333	.303	.272	.253	.225	.196	.323	.302	.281	.289	.258	.227
fatig(t − 1)	.512	.511	.511	.521	.520	.519	.522	.521	.520	.491	.490	.489	.488	.487	.487	.544	.540	.536
fatig(t − 2)	.393	.392	.391	.386	.385	.384	.382	.381	.380	.400	.399	.399	.405	.405	.404	.374	.372	.370
na(t − 1)	.041	.040	.039	.022	.021	.019	.011	.009	.007	.046	.046	.045	.017	.016	.015	.011	.008	.006
na(t − 2)	−.003	−.004	−.005	.005	.003	.002	.007	.006	.004	−.014	−.015	−.016	.017	.016	.015	.025	.023	.020
crav(t − 1)	−.003	−.003	−.004	−.013	−.013	−.013	.007	.006	.006	.008	.008	.008	.001	.000	.000	.012	.011	.010
crav(t − 2)	.011	.011	.011	.018	.018	.018	−.011	−.011	−.011	.006	.006	.006	−.002	−.003	−.003	−.009	−.010	−.010
se(t − 1)	−.016	−.017	−.017	.003	.002	.002	−.002	−.003	−.004	.006	.006	.005	−.001	−.002	−.003	−.021	−.026	−.030
se(t − 2)	.002	.001	.001	−.006	−.007	−.007	−.007	−.007	−.008	−.016	−.017	−.017	−.008	−.009	−.010	.017	.013	.010
Results for Equation (2): Predictors of Negative
Constant	.371	.354	.337	.143	.125	.134	.245	.228	.211	.213	.199	.185	.418	.398	.379	.733	.228	−.277
fatig(t − 1)	−.012	−.012	−.012	.018	.017	.018	.005	.005	.005	.028	.028	.028	−.007	−.007	−.007	.015	.008	.001
fatig(t − 2)	.048	.048	.048	.000	−.001	.000	.016	.016	.015	.005	.005	.004	.017	.017	.017	.007	.007	.006
na(t − 1)	.476	.475	.475	.489	.487	.488	.434	.433	.431	.387	.386	.385	.462	.461	.460	.454	.391	.327
na(t − 2)	.255	.254	.253	.291	.289	.290	.315	.314	.313	.318	.317	.315	.326	.325	.324	.503	.296	.089
crav(t − 1)	.021	.020	.020	.006	.006	.006	.022	.022	.022	.019	.019	.018	.007	.007	.007	.043	.021	.000
crav(t − 2)	.001	.001	.000	.006	.006	.006	−.002	−.002	−.002	.007	.007	.007	.006	.005	.005	.132	.028	−.077
se(t − 1)	−.022	−.022	−.022	−.024	−.024	−.024	−.014	−.014	−.014	−.001	−.001 −	.001	−.021	−.021	−.022	.155	.021	−.113
se(t − 2)	.001	.001	.001	.027	.027	.027	.007	.006	.006	.000	.000	.000	−.006	−.006	−.006	.062	−.028	−.117
Results for Equation (3): Predictors of Craving
Constant	1.519	1.448	1.376	1.578	1.515	1.451	1.458	1.366	1.274	1.438	1.354	1.27	1.661	1.583	1.504	1.349	1.185	1.021
fatig(t − 1)	−.001	−.002	−.003	.017	.016	.016	.023	.022	.021	.045	.044	.042	.001	.000	.000	.036	.033	.030
fatig(t − 2)	.034	.033	.032	.009	.009	.008	−.004	−.005	−.006	.005	.004	.003	.016	.016	.016	−.014	−.017	−.019
na(t − 1)	.076	.074	.073	.133	.130	.127	−.017	−.020	−.023	−.019	.022	−.026	.037	.034	.032	.042	.037	.031
na(t − 2)	−.012	−.014	−.016	−.029	−.033	−.036	.056	.053	.050	.082	.080	.077	.036	.034	.031	.020	.016	.012
crav(t − 1)	.429	.428	.427	.404	.403	.402	.433	.432	.432	.447	.446	.446	.410	.409	.408	.441	.439	.436
crav(t − 2)	.317	.316	.316	.295	.294	.293	.304	.303	.302	.308	.307	.305	.329	.328	.327	.349	.347	.346
se(t − 1)	−.018	−.020	−.021	−.088	−.090	−.091	−.087	−.088	−.089	−.033	−.034	−.035	−.031	−.032	−.034	−.067	−.068	−.070
se(t − 2)	−.046	−.047	−.049	.029	.028	.027	.031	.030	.029	−.032	.033	−.035	−.061	−.062	−.063	.018	.016	.015
Results for Equation (4): Predictors of Self-Efficacy
Constant	.969	.901	.833	.842	.799	.756	.928	.867	.805	1.036	.995	.953	1.171	1.117	1.064	1.488	.866	.244
fatig(t − 1)	.000	−.001	−.001	.005	.004	.004	−.002	−.003	−.003	−.013	−.013	−.013	.019	.018	.018	−.006	−.016	−.026
fatig(t − 2)	−.006	−.006	−.007	−.005	−.005	−.006	−.005	−.005	−.005	.011	.010	.010	−.020	−.021	−.021	.029	.013	−.003
na(t − 1)	.007	.006	.006	−.013	−.014	−.015	.007	.005	.004	.007	.006	.005	.000	−.001	−.002	.002	−.042	−.085
na(t − 2)	.003	.002	.001	.023	.022	.021	−.006	−.007	−.009	.012	.012	.011	−.003	−.004	−.005	.070	.034	−.002
crav(t − 1)	−.017	−.018	−.018	−.006	−.006	−.006	−.019	−.019	−.019	−.005	.005	−.006	−.019	−.019	−.019	−.028	−.034	−.040
crav(t − 2)	−.006	−.007	−.007	−.007	−.007	−.007	.008	.008	.007	−.005	.005	−.005	−.009	−.009	−.009	.014	.007	.001
se(t − 1)	.548	.547	.546	.553	.552	.551	.519	.518	.516	.554	.553	.551	.545	.544	.543	.489	.483	.477
se(t − 2)	.352	.351	.350	.351	.351	.350	.383	.382	.381	.331	.330	.329	.335	.334	.333	.418	.416	.414
Standard Errors of Noise from Disturbance Terms
σfatig		1.35			1.41			1.4			1.36			1.31			1.29
σna		1.41			1.46			1.47			1.44			1.36			1.38
σcrav		1.41			1.49			1.47			1.41			1.38			1.34
σse		1.34			1.4			1.4			1.35			1.31			1.3

Note: β̂₊ and β̂₋ represent the upper and lower 95% confidence limits for β̂, respectively