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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2017 Aug 25;180:215–222. doi: 10.1016/j.drugalcdep.2017.07.037

Table 2.

Predicted Values Across 60 Days for Each Treatment Group

Cessation Fatigue Difference
from
Placebo at
Day 60
Beginning Of Day 1. 2. 3. 5. 7. 10. 20. 30. 40. 60
Bupropion 2.990 3.049 3.104 3.174 3.200 3.186 3.015 2.891 2.835 2.805 0.334
Lozenge 2.990 2.986 2.974 2.932 2.880 2.804 2.634 2.569 2.546 2.537 0.066
Patch 2.990 2.963 2.923 2.834 2.745 2.626 2.380 2.287 2.255 2.243 −0.228
Patch+ Lozenge 2.990 2.965 2.927 2.830 2.723 2.569 2.223 2.093 2.053 2.039 −0.432
Bupropion+ Lozenge 2.990 2.974 2.947 2.875 2.791 2.668 2.381 2.266 2.229 2.215 −0.256
Placebo 2.990 3.000 2.996 2.968 2.924 2.850 2.644 2.538 2.494 2.471 0
Negative Affect
Bupropion 1.886 1.854 1.814 1.753 1.703 1.638 1.501 1.445 1.425 1.415 0.053
Lozenge 1.886 1.725 1.554 1.346 1.245 1.180 1.139 1.132 1.130 1.129 −0.233
Patch 1.886 1.766 1.643 1.477 1.379 1.293 1.18 1.149 1.140 1.137 −0.225
Patch+ Lozenge 1.886 1.744 1.624 1.489 1.419 1.355 1.248 1.214 1.204 1.201 −0.161
Bupropion+ Lozenge 1.886 1.858 1.809 1.696 1.583 1.440 1.194 1.127 1.111 1.105 −0.257
Placebo 1.886 1.780 1.698 1.607 1.558 1.509 1.414 1.379 1.367 1.362 0
Craving
Bupropion 4.881 5.012 5.099 5.106 5.013 4.842 4.483 4.361 4.321 4.304 0.005
Lozenge 4.881 4.924 4.874 4.710 4.545 4.356 4.090 4.025 4.008 4.003 −0.296
Patch 4.881 4.831 4.729 4.519 4.337 4.128 3.809 3.725 3.702 3.695 −0.604
Patch+ Lozenge 4.881 5.002 5.060 4.968 4.778 4.503 4.038 3.923 3.895 3.887 −0.412
Bupropion+ Lozenge 4.881 4.971 4.990 4.832 4.586 4.242 3.663 3.515 3.479 3.467 −0.832
Placebo 4.881 4.957 4.988 4.963 4.882 4.745 4.448 4.345 4.312 4.299 0
Self-Efficacy
Bupropion 4.083 4.441 4.863 5.563 6.082 6.625 7.419 7.632 7.693 7.718 0.475
Lozenge 4.083 4.433 4.856 5.565 6.097 6.658 7.461 7.658 7.707 7.722 0.479
Patch 4.083 4.457 4.896 5.649 6.222 6.831 7.719 7.945 8.003 8.023 0.78
Patch+ Lozenge 4.083 4.574 5.153 6.077 6.724 7.353 8.114 8.251 8.277 8.283 1.04
Bupropion+ Lozenge 4.083 4.549 5.092 5.962 6.581 7.201 8.03 8.219 8.264 8.277 1.034
Placebo 4.083 4.382 4.721 5.300 5.742 6.217 6.947 7.156 7.218 7.243 0