Table 1. Perioperative participant characteristics.
Data is mean (standard deviation) or number (proportion).
| Preoperative characteristics | Paracetamol (N = 25) | Saline (N = 25) | |
|---|---|---|---|
| Age (years) | 66.9 (11.9) | 67.8 (10.4) | |
| Male gender | 20 (80%) | 22 (88%) | |
| Weight (kg) | 82.3 (16.6) | 88.9 (17.8) | |
| Height (cm) | 172.2 (0.2) | 172.3 (9.7) | |
| Type of surgery | |||
| Coronary artery bypass graft | 16 (64%) | 15 (60%) | |
| Aortic valve replacement | 5 (20%) | 8 (32%) | |
| Mitral valve repair | 4 (16%) | 2 (8%) | |
| Coexisting conditions | |||
| Diabetes mellitus | 15 (60%) | 16 (64%) | |
| Peripheral arterial vascular disease | 18 (72%) | 20 (80%) | |
| Hypertension | 21 (84%) | 19 (76%) | |
| Chronic obstructive pulmonary disease | 10 (40%) | 9 (36%) | |
| Mild chronic renal impairment | 10 (40%) | 11 (44%) | |
| Euroscore II | 1.1 (0.6) | 1.5 (1.4) | |
| Intraoperative variables | P value | ||
| Surgery duration (mins) | 252.9 (48.9) | 257.1 (54.1) | 0.8 |
| Cardiopulmonary bypass time (mins) | 92.6 (21.9) | 99.4 (35.7) | 0.4 |
| Intraoperative fluid (mL) | 2015 (879) | 2209 (1107) | 0.5 |
| Intraoperative noradrenalin (ug) | 86 (140.3) | 192 (323.2) | 0.1 |
| Postoperative fluid (mL) | 3548 (1553) | 3213 (1177) | 0.4 |
| Postoperative noradrenalin (ug) | 1289 (2071) | 1682 (2470) | 0.5 |