Table 1.

Status of ATM, ATR, CHEK1, and CHEK2 genes in NB cells.

NB cell lines	ATM gene	Chromosomal coordinates of ATM loss/cnLOH	ATR gene	Chromosomal coordinates of ATR gain	CHEK1 gene	Chromosomal coordinates of CHEK1 loss/cnLOH	CHEK2 gene	Chromosomal coordinates of CHEK2 loss
SK-N-AS	Loss	Chr11: 72159638–134720344 Cytoband: 11q13.4–q25 Size: 62.5 Mb	Gain	Chr3: 94300781–197840323 Cytoband: 3q11.2–q29 Size: 103.5 Mb	Loss	Chr11: 72159638–134720344 Cytoband: 11q13.4–q25 Size: 62.5 Mb	Loss	Chr22: 23283056–31436822 Cytoband: 22q11.22–q12.2 Size: 8.1 Mb
SH-SY5Y	Single copy	—	Single copy	—	Single copy	—	Single copy	—
SH-EP	Loss	Chr11: 93455106–119038765 Cytoband: 11q21–q23.3 Size: 25.6 Mb	Gain	Chr3: 133671502–197801441 Cytoband: 3q22.1–q29 Size: 64.1 Mb	Single copy	—	Single copy	—
SK-N-SH	Single copy	—	Single copy	—	Single copy	—	Single copy	—
SK-N-BE(2)c	Copy-neutral LOH	Chr11: 55196818–134924542 Cytoband: 11q13.2–q24.3 Size: 79.7 Mb	Single copy	—	Copy neutral LOH	Chr11: 55196818–134924542 Cytoband: 11q13.2–q24.3 Size: 79.7 Mb	Loss	Chr22: 16153099–51224252 Cytoband: 22q11.1–q13.33 Size: 35.0 Mb
LA-N-5	Single copy	—	Single copy	—	Single copy	—	Single copy	—
IMR-32	Loss	Chr11: 85989063–134446160 Cytoband: 11q14.2–q25 Size: 48.4 Mb	Single copy	—	Loss	Chr11: 85989063–134446160 Cytoband: 11q14.2–q25 Size: 48.4 Mb	Single copy	—