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. 2018 Apr 16;13(4):e0196022. doi: 10.1371/journal.pone.0196022

Table 2. Crude associations between potential risk factors and mortality.

Total
(N = 450)
Completed
(n = 393)
Deceased
(n = 57)
Unadjusted OR (95% CI) P Value
Age ≥45 (years) 194 (43.1%) 157 (39.9%) 37 (64.9%) 2.78 (1.56, 4.97) 0.001
Male gender 346 (76.9%) 303 (77.1%) 43 (75.4%) 0.91 (0.48, 1.74) 0.78
Race/Ethnicity
 White 44 (9.8%) 37 (9.4%) 7 (12.3%) 1.22 (0.5, 2.99) 0.66
 Black 216 (48.0%) 187 (47.6%) 29 (50.9%) (ref)
 Hispanic 174 (38.7%) 155 (39.4%) 19 (33.3%) 0.79 (0.43, 1.46) 0.46
 Asian 14 (3.1%) 12 (3.1%) 2 (3.5%) 1.07 (0.23, 5.05) 0.93
 Other 2 (0.4%) 2 (0.5%) 0 (0.0%) -- --
US-born 266 (59.1%) 227 (57.8%) 39 (68.4%) 1.58 (0.88, 2.87) 0.13
Homeless 61 (13.6%) 48 (12.2%) 13 (22.8%) 2.12 (1.07, 4.23) 0.03
Resident of correction institution 35 (8.3%) 33 (9.0%) 2 (3.7%) 0.39 (0.09, 1.67) 0.20
Resident of long-term care facility 7 (1.6%) 3 (0.8%) 4 (7.0%) 9.81 (2.14, 45.05) 0.003
IDU 38 (8.4%) 31 (7.9%) 7 (12.3%) 1.63 (0.68, 3.91) 0.27
Excess alcohol use within past 12 months 144 (32.0%) 126 (32.1%) 18 (31.6%) 0.98 (0.54, 1.78) 0.94
History of diabetes 21 (4.7%) 13 (3.3%) 8 (14.0%) 4.77 (1.88, 12.09) 0.001
Chronic kidney failure 7 (1.6%) 4 (1.0%) 3 (5.3%) 5.4 (1.18, 24.8) 0.03
TB site 395 (87.8%) 347 (88.3%) 48 (84.2%) 0.71 (0.33, 1.54) 0.38
Meningeal TB 26 (5.8%) 18 (4.6%) 8 (14.0%) 3.4 (1.4, 8.24) 0.01
Miliary TB 40 (9.0%) 32 (8.3%) 8 (14.3%) 1.85 (0.81, 4.25) 0.15
TB-CXR 372 (85.7%) 323 (85.0%) 49 (90.7%) 1.73 (0.66, 4.53) 0.27
Cavitation on CXR 63 (16.9%) 60 (18.6%) 3 (6.1%) 0.29 (0.09, 0.95) 0.04
Positive AFB smear 173 (41.4%) 153 (41.0%) 20 (44.4%) 1.15 (0.62, 2.15) 0.66
Positive MTB culture 280 (67.6%) 244 (66.3%) 36 (78.3%) 1.83 (0.88, 3.81) 0.11
Sputum culture not converted or unknown 211 (46.9%) 168 (42.7%) 43 (75.4%) 4.11 (2.18, 7.76) <0.001
TB confirmed by positive culture or NAA 369 (82.0%) 317 (80.7%) 52 (91.2%) 2.49 (0.96, 6.46) 0.06
MDR-TB 1 (0.2%) 1 (0.3%) 0 (0.0%) --
East Asian lineage (L2) 75 (21.8%) 62 (20.9%) 13 (27.7%) 1.45 (0.72, 2.91) 0.30

IDU: injecting drug user; CXR: chest radiograph; NAA: Nucleic Acid Amplification; MDR-TB: Multi-drug resistant tuberculosis; excess alcohol use, having consumed five or more drinks on the same occasion on each of 5 or more days in the past 30 days, either self-reported or medically documented [12].