Table 2. Crude associations between potential risk factors and mortality.
Total (N = 450) |
Completed (n = 393) |
Deceased (n = 57) |
Unadjusted OR (95% CI) | P Value | |
---|---|---|---|---|---|
Age ≥45 (years) | 194 (43.1%) | 157 (39.9%) | 37 (64.9%) | 2.78 (1.56, 4.97) | 0.001 |
Male gender | 346 (76.9%) | 303 (77.1%) | 43 (75.4%) | 0.91 (0.48, 1.74) | 0.78 |
Race/Ethnicity | |||||
White | 44 (9.8%) | 37 (9.4%) | 7 (12.3%) | 1.22 (0.5, 2.99) | 0.66 |
Black | 216 (48.0%) | 187 (47.6%) | 29 (50.9%) | (ref) | |
Hispanic | 174 (38.7%) | 155 (39.4%) | 19 (33.3%) | 0.79 (0.43, 1.46) | 0.46 |
Asian | 14 (3.1%) | 12 (3.1%) | 2 (3.5%) | 1.07 (0.23, 5.05) | 0.93 |
Other | 2 (0.4%) | 2 (0.5%) | 0 (0.0%) | -- | -- |
US-born | 266 (59.1%) | 227 (57.8%) | 39 (68.4%) | 1.58 (0.88, 2.87) | 0.13 |
Homeless | 61 (13.6%) | 48 (12.2%) | 13 (22.8%) | 2.12 (1.07, 4.23) | 0.03 |
Resident of correction institution | 35 (8.3%) | 33 (9.0%) | 2 (3.7%) | 0.39 (0.09, 1.67) | 0.20 |
Resident of long-term care facility | 7 (1.6%) | 3 (0.8%) | 4 (7.0%) | 9.81 (2.14, 45.05) | 0.003 |
IDU | 38 (8.4%) | 31 (7.9%) | 7 (12.3%) | 1.63 (0.68, 3.91) | 0.27 |
Excess alcohol use within past 12 months | 144 (32.0%) | 126 (32.1%) | 18 (31.6%) | 0.98 (0.54, 1.78) | 0.94 |
History of diabetes | 21 (4.7%) | 13 (3.3%) | 8 (14.0%) | 4.77 (1.88, 12.09) | 0.001 |
Chronic kidney failure | 7 (1.6%) | 4 (1.0%) | 3 (5.3%) | 5.4 (1.18, 24.8) | 0.03 |
TB site | 395 (87.8%) | 347 (88.3%) | 48 (84.2%) | 0.71 (0.33, 1.54) | 0.38 |
Meningeal TB | 26 (5.8%) | 18 (4.6%) | 8 (14.0%) | 3.4 (1.4, 8.24) | 0.01 |
Miliary TB | 40 (9.0%) | 32 (8.3%) | 8 (14.3%) | 1.85 (0.81, 4.25) | 0.15 |
TB-CXR | 372 (85.7%) | 323 (85.0%) | 49 (90.7%) | 1.73 (0.66, 4.53) | 0.27 |
Cavitation on CXR | 63 (16.9%) | 60 (18.6%) | 3 (6.1%) | 0.29 (0.09, 0.95) | 0.04 |
Positive AFB smear | 173 (41.4%) | 153 (41.0%) | 20 (44.4%) | 1.15 (0.62, 2.15) | 0.66 |
Positive MTB culture | 280 (67.6%) | 244 (66.3%) | 36 (78.3%) | 1.83 (0.88, 3.81) | 0.11 |
Sputum culture not converted or unknown | 211 (46.9%) | 168 (42.7%) | 43 (75.4%) | 4.11 (2.18, 7.76) | <0.001 |
TB confirmed by positive culture or NAA | 369 (82.0%) | 317 (80.7%) | 52 (91.2%) | 2.49 (0.96, 6.46) | 0.06 |
MDR-TB | 1 (0.2%) | 1 (0.3%) | 0 (0.0%) | -- | |
East Asian lineage (L2) | 75 (21.8%) | 62 (20.9%) | 13 (27.7%) | 1.45 (0.72, 2.91) | 0.30 |
IDU: injecting drug user; CXR: chest radiograph; NAA: Nucleic Acid Amplification; MDR-TB: Multi-drug resistant tuberculosis; excess alcohol use, having consumed five or more drinks on the same occasion on each of 5 or more days in the past 30 days, either self-reported or medically documented [12].