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. Author manuscript; available in PMC: 2018 Apr 16.
Published in final edited form as: Lab Invest. 2017 Jun 5;97(7):843–853. doi: 10.1038/labinvest.2017.29

Figure 6.

Figure 6

Nf2;Notch2+/− and Nf2;Notch2 mice do not suffer severe liver damage. (a) Serum total bilirubin levels, (b) serum alanine aminotransferase (ALT) activity, (c) serum total bile acids levels in 8-week-old control, Nf2, Nf2;Notch2+/− and Nf2;Notch2 animals. Bars represent mean ± s.e.m. (n =3 mice from each genotype). *P<0.05, compared with control, #P<0.05, compared with Nf2, one-way ANOVA and Fisher's LSD. (d and e) Liver fibrosis evaluation of 8-week-old control, Nf2, Nf2;Notch2+/−, and Nf2;Notch2 animals with Sirius Red staining, a method detecting collagen deposition.