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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Prostaglandins Other Lipid Mediat. 2017 Sep 22;134:108–113. doi: 10.1016/j.prostaglandins.2017.09.004

Figure 1. Blood pressure and fetal death in NP and RUPP rats treated with HET0016.

Figure 1

(a). RUPP rats had significantly increased blood pressure compared to NP rats. RUPP rats treated with HET0016 had significantly lower blood pressure than untreated RUPPs. (b). Fetal death was increased with RUPP procedure compared to NP. HET0016 did not adversely affect fetal survival in NP and significantly improved survival in RUPP rats. (c). UARI was modestly increased in RUPP rats and decreased with HET0016 treatment. *P<0.05.