Table 2.
Changes in the T2D levels, hyperlipidemia levels, obesity levels, and pancreatic islet function levels of participants receiving JTTZ formula and metformin.
| JTTZ group | MET group | P values: week 12 in the JTTZ group versus MET group | P values: change in the JTTZ group versus MET group | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | Week 12 | Change from baseline to week 12 | P values: baseline versus week 12 | Baseline | Week 12 | Change from baseline to week 12 | P values: baseline versus week 12 | |||
| T2D levels | ||||||||||
| HbA1c (%) | 8.26 ± 1.35 | 7.51 ± 1.44 | −0.75 ± 1.32 | 0.000 | 8.28 ± 1.33 | 7.57 ± 1.42 | −0.71 ± 1.2 | 0.000 | 0.639 | 0.700 |
| FPG (mmol/L) | 9.64 ± 2.59 | 8.24 ± 2.35 | −1.4 ± 2.4 | 0.000 | 9.56 ± 2.39 | 8.21 ± 2.23 | −1.33 ± 2.33 | 0.000 | 0.865 | 0.781 |
| 2 h PG (mmol/L) | 16.76 ± 4.93 | 14.52 ± 4.73 | −2.42 ± 4.53 | 0.000 | 17.00 ± 4.72 | 14.83 ± 4.32 | −2.18 ± 4.48 | 0.000 | 0.500 | 0.606 |
| Hyperlipidemia levels | ||||||||||
| TG (mmol/L) | 3.43 ± 2.83 | 2.79 ± 1.86 | −0.64 ± 2.37 | 0.000 | 3.18 ± 2.14 | 2.82 ± 1.91 | −0.37 ± 2.18 | 0.018 | 0.889 | 0.227 |
| TC (mmol/L) | 5.46 ± 1.24 | 5.06 ± 1.00 | −0.39 ± 0.99 | 0.000 | 5.56 ± 1.36 | 5.21 ± 1.00 | −0.36 ± 1.16 | 0.000 | 0.147 | 0.764 |
| LDL-C (mmol/L) | 3.21 ± 0.96 | 2.92 ± 0.73 | −0.29 ± 0.79 | 0.000 | 3.29 ± 0.90 | 2.98 ± 0.76 | −0.31 ± 0.71 | 0.000 | 0.401 | 0.812 |
| Obesity levels | ||||||||||
| Weight (kg) | 77.82 ± 12.08 | 75.34 ± 12.05 | −2.47 ± 2.71 | 0.000 | 76.86 ± 12.06 | 74.83 ± 12.00 | −2.03 ± 2.36 | 0.000 | 0.666 | 0.093 |
| BMI (kg/m2) | 28.24 ± 3.31 | 27.33 ± 3.34 | −0.9 ± 0.99 | 0.000 | 28.01 ± 3.22 | 27.27 ± 3.21 | −0.74 ± 0.86 | 0.000 | 0.844 | 0.096 |
| Waist circumference (cm) | 97.25 ± 8.09 | 94.73 ± 8.29 | −2.52 ± 4.29 | 0.000 | 97.47 ± 9.24 | 94.98 ± 9.03 | −2.49 ± 3.86 | 0.000 | 0.774 | 0.946 |
| Hip circumference (cm) | 105.05 ± 7.14 | 102.02 ± 7.23 | −3.04 ± 3.86 | 0.000 | 105.31 ± 7.36 | 102.67 ± 7.16 | −2.65 ± 3.51 | 0.000 | 0.359 | 0.225 |
| Pancreatic islet function levels | ||||||||||
| HOMA-IR | 1.58 ± 0.72 | 1.39 ± 0.68 | −0.19 ± 0.91 | 0.005 | 1.5 ± 0.75 | 1.35 ± 0.67 | −0.16 ± 0.82 | 0.010 | 0.626 | 0.930 |
| HOMA-β | 3.73 ± 0.76 | 3.95 ± 0.76 | 0.26 ± 0.82 | 0.000 | 3.63 ± 0.78 | 3.91 ± 0.73 | 0.27 ± 0.87 | 0.000 | 0.638 | 0.752 |
Data presented as mean ± standard deviation. HbA1c: glycosylated hemoglobin; FPG: fasting plasma glucose; 2 h PG: 2 h postprandial plasma glucose; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; BMI: body mass index; HOMA-IR: insulin resistance index; HOMA-β: β cell function index.