Table 8.
Evaluation of acetylcholinesterase activity of Senna cana and Senna pendula extracts.
| Extracts | Qualitative analysis | Inhibition zone (mm) | Quantitative analysis (IC50 µg·mL−1)a |
|---|---|---|---|
| LEESC | Negative | — | 85.5 ± 0.05 |
| BEESC | Negative | — | 127.8 ± 0.09 |
| LHESC | Positive | 5 | 80.4 ± 0.001 |
| BHESC | Positive | 4 | 101.5 ± 0.03 |
| LEESP | Positive | 6 | 215.5 ± 0.05 |
| BEESP | Positive | 6 | 106.8 ± 0.06 |
| FEESP | Positive | 7 | 144.0 ± 0.06 |
| LHESP | Positive | 8 | 106.1 ± 0.02 |
| BHESP | Positive | 8 | 195.6 ± 0.002 |
| FHESP | Positive | 9 | 70.3 ± 0.001 |
| Standard (eserin) | Positive | 11 | 19.3 ± 0.05 |
aAcetylcholinesterase inhibition (AChEI) (IC50 µg·mL−1).