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. Author manuscript; available in PMC: 2019 Apr 5.
Published in final edited form as: Cell. 2018 Apr 5;173(2):338–354.e15. doi: 10.1016/j.cell.2018.03.034

Figure 2. Biological processes associated with cancer stemness.

Figure 2

(A) Gene Set Enrichment Analysis showing RNAseq-based stemness signature evaluated in the context of gene sets representative for Hallmarks of Stemness and Cancer.

(B) Correlation between mRNAsi and mRNA expression for published hallmarks of stemness.

(C) Correlation between mRNAsi and selected oncogenic processes.

(D) Association between the epigenomic-based stemness signature (EREG-mDNAsi and EREG-mRNAsi) and enrichment in the transcription factor binding sites.

See also Figure S2 and Table S2.