Figure 1.

Expression of miR-326 in glioblastoma cells treated with miR-326 mimics, curcumin, or both, and the effect of miR-326 on the chemosensitivity of U87 and U251 cells to curcumin. (A) RT-PCR results of the expression of miR-326 in cells treated with different doses of curcumin and/or miR-326 mimics. (B) U87 and U251 cells were treated with miR-326 and/or increasing concentrations of curcumin for 24 h. Viability was analyzed using the MTT assay. The data represent the mean ± SEM of 3 replicates. Statistical significance levels are indicated as: *P < 0.05; **P < 0.01 and ***P < 0.001