Figure 5.

Schematic diagram of the gene clusters encoding proteins involved in the biogenesis of fimbriae in JS14 and JS22. Genes encoding fimbrial shaft protein (FimA) and tip fimbrillin (FimB) subunits, and a fimbria‐specific sortase (SrtC) are shown. Conserved features required for fimbriae (E‐box, LXET; pilin motif, YPKN) (Persson et al., 2012) are found in FimA or FimB. The LPxTG‐motif required for sortase‐mediated protein ligation was found in small ORFs following FimA (JS22 and JS14) or the truncated FimB‐encoding genes (JS14). SrtC was characterized by the presence of a C‐terminal hydrophobic membrane anchoring domain.