Table 3.
Genetic testing to lab report issued | Women with known genetic testing outcome | Included womena | Median (days) | IQR (days) | 90th Percentile (days) | p‐Value |
---|---|---|---|---|---|---|
Program year | ||||||
2011–2012 (reference) | 1,854 | 1,818 | 43 | 25–75 | 124 | — |
2012–2013 | 2,162 | 2,144 | 44 | 23–71 | 107 | .896 |
2013–2014 | 2,187 | 2,156 | 36 | 20–67 | 105 | <.0001 |
2014–2015 | 2,241 | 2,212 | 41 | 22–70 | 94 | .0008 |
Age groupb | ||||||
30–49 years (reference) | 3,781 | 3,726 | 36 | 20–63 | 97 | — |
50–69 years | 4,663 | 4,604 | 45 | 26–76 | 110 | <.0001 |
Prior breast cancer | ||||||
No (reference) | 6,854 | 6,760 | 39 | 21–66 | 102 | — |
Yes | 1,590 | 1,570 | 49 | 30–84 | 114 | <.0001 |
Risk criteriac | ||||||
Gene mutation carrier (reference) | 1,278 | 1,256 | 33 | 19–58 | 91 | — |
Family history and ≥25% riskd | 535 | 528 | 41 | 20–73 | 100 | .0005 |
Ineligible for high risk screening | 6,604 | 6,519 | 43 | 23–72 | 107 | <.0001 |
Excludes women who had laboratory report result entered prior to their genetic testing (n = 86) or women who had >365 days between genetic test and laboratory report issued (n = 28).
At time of High Risk OBSP referral.
If a woman met more than one risk criterion after genetic assessment, the following hierarchy was selected: carrier of a deleterious gene mutation, family history and ≥25% lifetime risk, first‐degree relative of a mutation carrier (but declined genetic testing); women who are a first‐degree relative of a mutation carrier (but declined genetic testing) were excluded (n = 27).
Based on International Breast Cancer Intervention Study (IBIS) and/or Breast and Ovarian Analysis of Disease Incidence of Carrier Estimation Algorithm (BOADICEA).