Table 3.
Distribution of GPX1 Pro198Leu polymorphism according to familial history of breast cancer
| Cases | n | Genotype | Allele | ||
|---|---|---|---|---|---|
| Pro/Pro % [95% CI] | Pro/Leu % [95% CI] | Pro% [95% CI] | Leu % [95% CI] | ||
| Cases with familial history | 13 | 46.1 [36.66–55.83] | 53.9 [44.17–63.34] | 73.1 [63.63–80.86] | 26.9 [19.14–36.37] |
| Sporadic cases | 28 | 50 [40.38–59.62] | 50 [40.38–59.62] | 75 [65.65–82.5] | 25 [17.5–34.35] |
| p a | .340 | .442 | |||
rs1050450 C>T (NM_001329455.1).
CI, confidence intervals; n, number.
a
No case has the Leu/Leu genotype; therefore this genotype was not included in the statistical analysis.