Table 11.
Comparison of KIRREL3 patients to ASD cohort
| KIRREL3 (percent) N = 6 | Other ASD (percent) N = 94 | p value | |
|---|---|---|---|
| Intellectual disability (IQ < 70) | 6 (100) | 50/82 (61) | .06 |
| ADOS comparison score 9–10 | 2 (33) | 51/92 (55) | NS |
| Regression | 2 (33) | 14/79 (18) | NS |
| Seizures | 0 | 11/90 (12) | NS |
| Dysmorphic features | 4 (67) | 33/89 (37) | NS |
| Family history of ASD (parent/sibling) | 4 (67) | 18/93 (19) | .02a |
| Family history of psychiatric disease (parent/sibling) | 2 (33) | 33/93 (35) | NS |
NS, not significant.
a
Indicates finding is significant.