Table 4.
Cause of Death, No (%) | TBI, N=377 deaths | BU, N=135 deaths |
---|---|---|
Relapse | 170 (45) | 77 (57) |
Graft failure | 2 (0.5) | 0 (0) |
GVHD | 50 (13) | 16 (11.8) |
Infection | 51 (13) | 8 (5.9) |
Interstitial pneumonitis or ARDS | 19 (5) | 1 (0.7) |
Organ failure | 45 (12) | 12 (8.8) |
Secondary malignancy | 3 (0.7) | 1 (0.7) |
Hemorrhage | 3 (0.7) | 1 (0.7) |
Accident | 1 (0.2) | 0 (0) |
Vascular | 1 (0.2) | 1 (0.7) |
Other | 23 (6.1) | 15 (11) |
Unknown | 9 (2.4) | 3 (2.2) |
Abbreviations: GVHD, graft-versus-host disease; TBI, total body irradiation; BU, busulfan; N, number; ARDS, acute respiratory distress syndrome