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. 2018 Apr 10;9:603. doi: 10.3389/fmicb.2018.00603

Table 5.

Invasion and translocation ability of SBSEC species in different cell lines.

SBSEC species with invasion or translocation % (no. of strains invasion or translocation positive/total no. of strains)
Cell line SGG SGM SL Isolation sources Comments References
Invasion
CRC CELL LINES
Human Caco-2 0% (0/3) Human blood SGG UCN34, 1293, NTB1 Boleij et al., 2011b
0% (0/1) Human feces SGG NCTC8133 Boleij et al., 2011b
0% (0/1) Dairy SGM CIP105865T Boleij et al., 2011b
82% (14/17) Sea otter IE Only 1 strain with 0.2% invasion, all others low invasion Counihan et al., 2015
100% (1/1) Sea otter feces Low invasion Counihan et al., 2015
100% (1/1) Sea otter brain Low invasion Counihan et al., 2015
100% (1/1) Sea otter lymph Low invasion Counihan et al., 2015
100% (1/1) Sea otter ulcer Low invasion Counihan et al., 2015
0% (0/2) Bovine feces Low invasion Sánchez-Díaz et al., 2016
0% (0/2) Human blood Low invasion Sánchez-Díaz et al., 2016
Human HCT116 0% (0/2) Human IE SGG TX20005, TX20030, considered as low to non-invasive Kumar et al., 2017
Human HT-29 0% (0/2) Human IE SGG TX20005, TX20030, considered as low to non-invasive Kumar et al., 2017
Human SW1116 0% (0/2) Human IE SGG TX20005, TX20030, considered as low to non-invasive Kumar et al., 2017
Human SW480 0% (0/2) Human IE SGG TX20005, TX20030, considered as low to non-invasive Kumar et al., 2017
ENDOTHELIAL CELL LINES
Human 494 umbilical vein HUVEC 76% (13/17) Sea otter IE Low invasion Counihan et al., 2015
100% (1/1) Sea otter feces Low invasion Counihan et al., 2015
0% (0/1) Sea otter brain Low invasion Counihan et al., 2015
100% (1/1) Sea otter lymph Low invasion Counihan et al., 2015
100% (1/1) Sea otter ulcer Low invasion Counihan et al., 2015
100% (5/5) Human clinical IE/blood/other Vollmer et al., 2010
0% (0/1) Koala feces SGG DSM16831T Vollmer et al., 2010
Human vascular endothelial EA.hy926 100% (21/21) Human clinical IE/blood/other Vollmer et al., 2010
0% (0/1) Koala feces SGG DSM16831T Vollmer et al., 2010
100% (1/1) Shea cake digester SGG DSM13808 Vollmer et al., 2010
OTHER CELL LINES
Human lung carcinoma A549 0% (0/2) Human IE SGG TX20005, TX20030, considered as low to non-invasive Kumar et al., 2017
Human normal colon epithelial cell line CCD 841 CoN 0% (0/2) Human IE SGG TX20005, TX20030, considered as low to non-invasive Kumar et al., 2017
Translocation
CRC CELL LINE
Human Caco-2 epithelial monolayer 50% (1/2) Bovine feces Sánchez-Díaz et al., 2016
100% (2/2) Human blood Sánchez-Díaz et al., 2016
100% (3/3) Human blood SGG UCN34, 1293, NTB1 Boleij et al., 2011b
100% (1/1) Human feces SGG NCTC8133 Boleij et al., 2011b
0% (0/1) Dairy SGM CIP105865T Boleij et al., 2011b