Table 5.
Invasion and translocation ability of SBSEC species in different cell lines.
| SBSEC species with invasion or translocation % (no. of strains invasion or translocation positive/total no. of strains) | ||||||
|---|---|---|---|---|---|---|
| Cell line | SGG | SGM | SL | Isolation sources | Comments | References |
| Invasion | ||||||
| CRC CELL LINES | ||||||
| Human Caco-2 | 0% (0/3) | – | – | Human blood | SGG UCN34, 1293, NTB1 | Boleij et al., 2011b |
| 0% (0/1) | – | – | Human feces | SGG NCTC8133 | Boleij et al., 2011b | |
| – | 0% (0/1) | – | Dairy | SGM CIP105865T | Boleij et al., 2011b | |
| – | – | 82% (14/17) | Sea otter IE | Only 1 strain with 0.2% invasion, all others low invasion | Counihan et al., 2015 | |
| – | – | 100% (1/1) | Sea otter feces | Low invasion | Counihan et al., 2015 | |
| – | – | 100% (1/1) | Sea otter brain | Low invasion | Counihan et al., 2015 | |
| – | – | 100% (1/1) | Sea otter lymph | Low invasion | Counihan et al., 2015 | |
| – | – | 100% (1/1) | Sea otter ulcer | Low invasion | Counihan et al., 2015 | |
| 0% (0/2) | – | – | Bovine feces | Low invasion | Sánchez-Díaz et al., 2016 | |
| 0% (0/2) | – | – | Human blood | Low invasion | Sánchez-Díaz et al., 2016 | |
| Human HCT116 | 0% (0/2) | – | – | Human IE | SGG TX20005, TX20030, considered as low to non-invasive | Kumar et al., 2017 |
| Human HT-29 | 0% (0/2) | – | – | Human IE | SGG TX20005, TX20030, considered as low to non-invasive | Kumar et al., 2017 |
| Human SW1116 | 0% (0/2) | – | – | Human IE | SGG TX20005, TX20030, considered as low to non-invasive | Kumar et al., 2017 |
| Human SW480 | 0% (0/2) | – | – | Human IE | SGG TX20005, TX20030, considered as low to non-invasive | Kumar et al., 2017 |
| ENDOTHELIAL CELL LINES | ||||||
| Human 494 umbilical vein HUVEC | – | – | 76% (13/17) | Sea otter IE | Low invasion | Counihan et al., 2015 |
| – | – | 100% (1/1) | Sea otter feces | Low invasion | Counihan et al., 2015 | |
| – | – | 0% (0/1) | Sea otter brain | Low invasion | Counihan et al., 2015 | |
| – | – | 100% (1/1) | Sea otter lymph | Low invasion | Counihan et al., 2015 | |
| – | – | 100% (1/1) | Sea otter ulcer | Low invasion | Counihan et al., 2015 | |
| 100% (5/5) | – | – | Human clinical IE/blood/other | Vollmer et al., 2010 | ||
| 0% (0/1) | – | – | Koala feces | SGG DSM16831T | Vollmer et al., 2010 | |
| Human vascular endothelial EA.hy926 | 100% (21/21) | – | – | Human clinical IE/blood/other | Vollmer et al., 2010 | |
| 0% (0/1) | – | – | Koala feces | SGG DSM16831T | Vollmer et al., 2010 | |
| 100% (1/1) | – | – | Shea cake digester | SGG DSM13808 | Vollmer et al., 2010 | |
| OTHER CELL LINES | ||||||
| Human lung carcinoma A549 | 0% (0/2) | – | – | Human IE | SGG TX20005, TX20030, considered as low to non-invasive | Kumar et al., 2017 |
| Human normal colon epithelial cell line CCD 841 CoN | 0% (0/2) | – | – | Human IE | SGG TX20005, TX20030, considered as low to non-invasive | Kumar et al., 2017 |
| Translocation | ||||||
| CRC CELL LINE | ||||||
| Human Caco-2 epithelial monolayer | 50% (1/2) | – | – | Bovine feces | Sánchez-Díaz et al., 2016 | |
| 100% (2/2) | – | – | Human blood | Sánchez-Díaz et al., 2016 | ||
| 100% (3/3) | – | – | Human blood | SGG UCN34, 1293, NTB1 | Boleij et al., 2011b | |
| 100% (1/1) | – | – | Human feces | SGG NCTC8133 | Boleij et al., 2011b | |
| – | 0% (0/1) | – | Dairy | SGM CIP105865T | Boleij et al., 2011b | |