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. 2018 Apr 10;9:710. doi: 10.3389/fmicb.2018.00710

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Copyright © 2018 Ji, Park, Park, Hwang, Shin, Pot and Holzapfel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fecal microbiota of LFD, HFD, and HFD+LGG groups. Black colored circle, rectangle, and triangle illustrate results of DNA analysis while empty symbols illustrate results of RNA analysis. (A) Firmicutes, Bacteroidetes, and Firmicutes over Bacteroidetes ratio (F/B); (B) major sub-groups of Firmicutes; (C) major sub-groups of Bacteroidetes. Significance level was calculated using ANOVA and Bonferroni’s multiple comparisons test and ^∗ shows significant difference between DNA and RNA analysis, $ shows significant difference of LFD and HFD+LGG compared to HFD according to DNA analysis and # shows significant difference of LFD and HFD+LGG compared to HFD according to RNA analysis. The level of significance is expressed by the number of symbols (one = <0.05, two = <0.01, three = <0.001).