Table 1.
Baseline Demographic Characteristics of SLE patients with and without DM.
| DM (N = 1317) | Non-DM (N = 1317) | P-value | |
|---|---|---|---|
| Age at SLE, years (mean ± SD) | 44.56 ± 15.06 | 44.56 ± 15.06 | 0.99 |
| Age at index date, years (mean ± SD) | 48.52 ± 14.99 | 48.52 ± 14.99 | 0.99 |
| Age at index date (n, %) | >0.99 | ||
| <45 | 541 (41.08) | 541 (41.08) | |
| 45–65 | 576 (43.74) | 576 (43.74) | |
| ≥65 | 200 (15.19) | 200 (15.19) | |
| Duration from SLE date to index date, years (mean ± SD) | 3.97 ± 2.93 | 3.97 ± 2.93 | >0.99 |
| Female (n, %) | 1198 (90.96) | 1198 (90.96) | >0.99 |
| Baseline comorbidity (n, %) | |||
| Hypertension | 412 (31.28) | 55 (4.18) | <0.0001 |
| CAD | 83 (6.30) | 14 (1.06) | <0.0001 |
| Hyperlipidemia | 140 (10.63) | 14 (1.06) | <0.0001 |
| Gout | 41 (3.11) | 5 (0.38) | <0.0001 |
| HBV infection | 16 (1.21) | 4 (0.30) | 0.007 |
| HCV infection | 22 (1.67) | 3 (0.23) | 0.0001 |
| Cirrhosis | 26 (1.97) | 3 (0.23) | 0.001 |
SLE: systemic lupus erythematosus; CAD: coronary artery disease; HBV infection: hepatitis B virus infection; HCV infection: hepatitis C virus infection; SD: standard deviation.
Between DM patients and controls cohorts, the differences in categorical variables were compared using Chi-square tests or fisher’s exact test and the differences in continuous variables were compared using Student’s t-test.