Table 3.
Crude and adjusted hazard ratios of Cox proportional hazard regressions and 95% confidence interval for ESRD during the follow-up period for study cohort.
| Variable | Crude Hazard Ratio (95% CI) | Adjusted Hazard Ratio (95% CI) |
|---|---|---|
| DM (yes vs. no) | 2.71 (1.70–4.33)* | 1.64 (0.97–2.76) |
| Age at index date | ||
| <45 | 1.00 | 1.00 |
| 45–65 | 0.92 (0.58–1.45) | 0.71 (0.44–1.14) |
| ≥65 | 1.13 (0.63–2.02) | 0.74 (0.40–1.37) |
| Female (vs. male) | 0.72 (0.38–1.35) | 0.74 (0.40–1.40) |
| Comorbidity | ||
| Hypertension (yes vs. no) | 4.30 (2.84–6.53)* | 3.29 (1.98–5.47)* |
| CAD (yes vs. no) | 0.85 (0.27–2.68) | 0.35 (0.11–1.16) |
| Hyperlipidemia (yes vs. no) | 3.73 (2.14–6.51)* | 1.77 (0.96–3.27) |
| Gout (yes vs. no) | 6.90 (3.46–13.77)* | 3.06 (1.46–6.42)* |
| HBV (yes vs. no) | N/A | N/A |
| HCV (yes vs. no) | 0.64 (0.22–11.28) | 1.22 (0.17–8.96) |
| Cirrhosis (yes vs. no) | 0.00 (0.00 - Inf) | 0.82 (0.11–6.01) |
DM: diabetes mellitus; CAD: coronary artery disease; HBV infection: hepatitis B virus infection; HCV infection: hepatitis C virus infection.
*p-value < 0.05. CI: Confidence interval.