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. 2018 Apr 16;8:6034. doi: 10.1038/s41598-018-24380-5

Table 1.

Impact of hadD deletion on the sensitivity of M. smegmatis to antibiotics and SDS in planktonic cultures.

M. smegmatis strain Minimal inhibitory concentrationa
Rifampicin (µg/ml) Isoniazid (µg/ml) Ethambutol (µg/ml) SDS (%)
wt 16.9 ± 4.8 7.1 ± 0.9 3.9 ± 1.2 0.016 ± 0.000
ΔhadD 0.37 ± 0.13 7.7 ± 0.2 3.1 ± 0.0 0.007 ± 0.001
complemented 3.1 ± 0.9 6.4 ± 1.6 3.1 ± 0.0 0.012 ± 0.004

aMIC values (means ± average deviations) measured by MTT assays were determined as the lowest concentration of compound yielding 99.9% inhibition of the bacterial growth.