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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2017 Dec 6;24(4):678–686. doi: 10.1016/j.bbmt.2017.11.039

Figure 4. Prognostic values by prevalence of IPS.

Figure 4

Negative Predictive Value (NPV, left panels) and Positive Predictive Value (PPV, right panels) curves for each biomarker are shown for predicting IPS at the day of onset or day 7 after HCT. Predictive values were calculated using the sensitivity and specificity values from the points closest to the top left corner of the ROC curves and are estimated for a range of hypothetical IPS prevalence values (x-axis).

Abbreviations: IPS, idiopathic pneumonia syndrome; HCT, hematopoietic cell transplantation; ROC, receiver operating characteristic; HRV, human rhinovirus; PIV, parainfluenza virus; EPCR, endothelial protein C receptor; HVEM, herpes virus entry mediator; IL-6, interleukin-6; LYVE1, lymphocyte vessel endothelial receptor; ST2, Stimulation 2; TNFR1, tumor necrosis factor receptor 1.