Schematic diagram of the nephrovascular unit represented in the simplified model. Perturbations from the reference state: δΛ, perfusion pressure; q, blood flow; p, blood pressure; qF, SNGFR; c, macula densa [Cl−]; v, smooth muscle membrane potential; u, smooth muscle activation; εw, vascular resistance. Currents mediating the myogenic response and tubuloglomerular feedback are denoted by iMR and iTGF, respectively (Color figure online)