Table 1.

Characteristics of PSMA aptamers and truncated aptamers

Aptamer	Sequence	Bases	Affinity	Ref
40N7 Library	GGGAGGACGAUGCGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCAGACGACUCGCCCGA	71	N.A.	[13]
xPSM-A9	GGGAGGACGAUGCGGACCGAAAAAGACCUGACUUCUAUACUAAGUCUACGUUCCCAGACGACUCGCCCGA	70	1.1 nM (Ki)	[13,16]
			110 nM (Kd SBA)
xPSM-A10	GGGAGGACGAUGCGGAUCAGCCAUGUUUACGUCACUCCUUGUCAAUCCUCAUCGGCAGACGACUCGCCCGA	72	11.9 nM (Ki)	[13,17]
			1.5 nM (Kd CBA)
A10-3	GGGAGGACGAUGCGGAUCAGCCAUGUUUACGUCACUCCUUGUCAAUCCUCAUCGGC	56	1.1 nM (Ki)	[13,17]
			0.5 nM (Kd CBA)
A10-3.2	GGGAGGACGAUGCGGAUCAGCCAUGUUUACGUCACUCCU	39	2.9 nM (Kd CBA)	[17]
A9g	GGGACGGAAAAAGACCUGACUUCUAUACUAAGUCUACGUUCCC	43	130 nM (Kd SBA)	[16]
			5 nM (Kd SPR)
A9L	GGGCCGAAAAAGACCUGACUUCUAUACUAAGUCUACGUCCC	41	N.D.	[16]

K_i, Determined by enzymatic Inhibition assay; SBA, Saturation Filter Binding Assay; CBA, Cell Binding Assay; SPR, Surface Plasmon Resonance.